Telomeres: Chromosome Sentinels
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Telomeres are specialized DNA–protein structures that protect the ends of chromosomes to maintain their integrity. They are chromosome sentinels. This book, written by multiple authors, presents current knowledge and the most recent discoveries relating to telomeres.
The first chapters describe telomere structures (DNA and proteins), organization, dynamics and replication in a range of organisms including ciliates, yeast and mammals. The following chapters cover mechanisms that maintain telomere length involving telomerase and Alternative Lengthening Telomeres (ALT) mechanisms. Interestingly, telomeres are transcribed into repetitive RNA called TERRA (Telomeric repeat-containing RNA), the state of the art regarding mammalian telomere transcripts is presented here.
Two chapters are dedicated to the description of how telomere biology impacts the development of cancer and how their disfunctions induce telomeropathies (telomere biology disorders). Finally, the book ends with a chapter presenting telomere and telomerase targeting agents as potential anticancer agents, a promising therapeutic approach.
Details
- Publisher
- Wiley
- Format
- Hardcover
- Published
- Jul 23, 2024
- ISBN-13
- 9781789450972
- Pages
- 400
- Printing
- Printed on demand
Telomeres for groups: pricing
Volume pricing applies automatically in your cart. No codes, no account needed.
| Copies | Price per copy | You save |
|---|---|---|
| 25 – 99 | $144.50 | 15% off list |
| 100 – 249 | $142.80 | 16% off list |
| 250 – 499 | $141.10 | 17% off list |
| 500 – 999 | $139.40 | 18% off list |
| 1,000+ | $136.00 | 20% off list |
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BookPal sells Telomeres in quantity. At 100 copies the price is $142.80 a copy, against a list price of $170.00, and the cart applies the volume tier automatically. Free shipping on most orders over $95 in the contiguous US. A specialist can quote a larger or mixed order.
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What does Telomeres cost when I buy for a group?
Volume pricing applies automatically in your cart, with no code needed. Price per copy: 25 to 99 copies, $144.50 (15% off list); 100 to 249 copies, $142.80 (16% off list); 250 to 499 copies, $141.10 (17% off list); 500 to 999 copies, $139.40 (18% off list); 1,000+ copies, $136.00 (20% off list). Need a different quantity, or a quote to forward for approval? Ask a specialist and we will confirm pricing before you pay.
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Telomeres: Chromosome Sentinels
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