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Tumor Microenvironment (Cancer Treatment and Research #180) book cover by
Paperback

Tumor Microenvironment (Cancer Treatment and Research #180)

$86.39 / copy at 25+ copies As low as $84.59 at 100+Your best volume price

Total $2,159.75

Paperback · 326 pages Springer International Publishing · 2021

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Paperback
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About the book

Tumor Microenvironment (Cancer Treatment and Research #180)

This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. 

The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. 

Understanding the major requirements for the evolutionary process governing human cancer growth in the immune-competent host will guide effective therapeutic choices that are tailored to the biology of individual cancers.



Details

Publisher
Springer International Publishing
Format
Paperback
Published
Mar 26, 2021
ISBN-13
9783030388645
Pages
326
Printing
Printed on demand
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Tumor Microenvironment (Cancer Treatment and Research #180) for groups: pricing

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CopiesPrice per copyYou save
25 – 49 $86.39 4% off list
50 – 99 $85.49 5% off list
100+ $84.59 6% off list
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