Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology
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Discover an enhanced synthetic approach to developing and screening chemical compound libraries
Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.
Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book:
- Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles
- Expands on the concept of diversity-oriented synthesis by describing chemical libraries
- Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays
- Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research
This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.
Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.
The book, Diversity-Oriented Synthesis: Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology [Bulk, Wholesale, Quantity] ISBN#9781118145654 in Hardcover by Andrea Trabocchi may be ordered in bulk quantities. Minimum starts at 25 copies. Availability based on publisher status and quantity being ordered.
Details
- Publisher
- Wiley
- Author
- Andrea Trabocchi
- Format
- Hardcover
- Published
- Jul 15, 2013
- ISBN-13
- 9781118145654
- Pages
- 680
- Carton quantity
- 12 copies
- Printing
- Printed on demand
Diversity-Oriented Synthesis in bulk: pricing
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| Copies | Price per copy | You save |
|---|---|---|
| 25 – 99 | $157.21 | 15% off list |
| 100 – 249 | $155.36 | 16% off list |
| 250 – 499 | $153.51 | 17% off list |
| 500 – 999 | $151.66 | 18% off list |
| 1,000+ | $147.96 | 20% off list |
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